A crazy group of pioneers brave the harsh elements and numerous mishaps to travel thousands of miles out west to find a place to call home.

Embezzler, shill, all around confidence man S. Quentin Quale is heading west to find his fortune; he meets the crafty but simple brothers Joseph and Rusty Panello in a train station, where they steal all his money. They’re heading west, too, because they’ve heard you can just pick the gold off the ground. Once there, they befriend an old miner named Dan Wilson whose property, Dead Man’s Gulch, has no gold. They loan him their last ten dollars so he can go start life anew, and for collateral, he gives them the deed to the Gulch. Unbeknownst to Wilson, the son of his longtime rival, Terry Turner (who’s also in love with his daughter, Eva), has contacted the railroad to arrange for them to build through the land, making the old man rich and hopefully resolving the feud. But the evil Red Baxter, owner of a saloon, tricks the boys out of the deed, and it’s up to them – as well as Quale, who naturally finds his way out west anyway – to save the day.

With little luck at keeping a job in the city a New Yorker tries work in the country and eventually finds his way leading a herd of cattle to the West Coast.